Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)


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Friedmann T, Roblin R.


  1. Clinical use of lentiviral vectors?
  2. Tectonic and stratigraphic evolution of zagros and makran during the mesozoic-cenozoic!
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Vectors in gene therapy - Wikipedia

Mol Pharm. Gene therapy: therapeutic gene causing lymphoma. Gao X, Huang L. Potentiation of cationic liposome-mediated gene delivery by polycations. Stem cell gene transfer--efficacy and safety in large animal studies. The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Trends Mol Med. Sci Transl Med. Effect of selective LRRK2 kinase inhibition on nonhuman primate lung.

Methods Mol Biol. JAMA Neurol.

Virology Lectures 2018 #24: Viral Gene Therapy

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Gene therapy for carcinoma of the breast. Cancer Gene Ther. Gene therapy for cancer: regulatory considerations for approval. Gene therapy clinical trials worldwide to An update. J Gene Med. Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome. Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndrome. Transfusion independence and HMGA2 activation after gene therapy of human beta-thalassaemia.

Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy. Lentiviral hematopoietic cell gene therapy for X-linked adrenoleukodystrophy.

Link to external resource:

Methods Enzymol. Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy. Replication of plasmids derived from bovine papilloma virus type 1 and Epstein-Barr virus in cell in culture.

Associated Data

Annu Rev Cell Biol ; Micro Nano Mechatron Hum Sci ; Biochem Biophys Res Commun ; Epstein-Barr virus vectors for gene delivery to B lymphocytes. In vivo characteristics of cationic liposomes as delivery vectors for gene therapy. Pharm Res ; Quantitative analysis of synthesis gene delivery vector design properties. Long term persistence of plasmid DNA and foreign gene expression in mouse muscle. Hum Mol Genet ; Knapp JE, Liu D.


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  • Hydrodynamic delivery of DNA. Herweijer H, Wolff JA. Progress and prospects: Naked DNA gene transfer and therapy.

    Progress and problems with the use of viral vectors for gene therapy

    Gen Ther ; In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment. Transformation of microbes, plants and animals by particle bombardment. Biotechnology ; In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment. DNA cancer vaccines: A gene gun approach. Immunol Cell Biol ; Electroporation for targeted gene transfer.

    Expert Opin Drug Deliv ; Lurquin PF. Gene transfer by electroporation. Potter H, Cooke SW.

    Developing gene therapy to treat cystic fibrosis: challenges and successes

    Gene transfer into adherent cells growing on microbeads. In: Change DC, editor. Guide to electroporation and electrofusion. Gene transferin to mouse lyoma cells by electroporation in high electric fields. EMBOJ ; Electroporation as a method for high level nonviral gene transfer to the lung. Electroporation for gene transfer to skeletal muscles: Current status. Biol Drugs ; Gene correction in hematopoietic progenitor cells by homologous recombination.

    Electroporation therapy of solid tumors. Gissel H, Clausen T.

    Excitation -induced Ca influx and skeletal muscle cell damage. Acta Physiol Scand ; Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. High level factor VIII gene expression in vivo achieved by nonviral liver-specific gene therapy vectors. Hum Gen Ther ; Intravenous delivery of naked plasmid DNA for in vivo cytokine expression. Rat liver targeted naked plasmid DNA transfer by tail vein injection.

    Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth. Hepatology ; Ultrasound-mediated transfection of mammalian cells. Optimisation of ultrasound mediated gene transfer sonoporation in skeletal muscle cells. Ultrasound Med Biol ; The magnetofection method: Using magnetic force to enhance gene delivery. Biol Chem ; Magnetofection: Enhancing and targeting gene delivery by magnetic force in vitro and in vivo. Enhancing and targeting nucleic acid delivery by magnetic force.

    J Biomed Nanotechnol ; Cationic transfection lipids. Curr Med Chem ; Cationic compounds used in lipoplexes and polyplexes for gene delivery. J Controlled Release ; Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery. Pharmacol Rev ; Boeckle S, Wagner E. Optimizing targeted gene delivery: Chemical Modification of viral vectors and synthesis of artificial virus vector systems.

    Bioconjug Chem ; Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice. Transferrin-liposome-mediated systemic p53 gene therapy in combination with radiation results in regression of human head and neck cancer xenografts. Tumor-targeted gene delivery via anti-HER2 antibody trastuzumab, Herceptin conjugated polyethylenimine. J Control Release ; Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer. Clin Cancer Res ; Tumor regression by targeted gene delivery to the neovasculature.

    Gene transfer into hepatocytes using asialoglycoprotein receptor-mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand1.

    Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine) Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)
    Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine) Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)
    Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine) Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)
    Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine) Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)
    Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine) Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)
    Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine) Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)
    Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine) Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)

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